Wednesday, October 16, 2013

Wagner, one of the biggest advocates of the use of umbilical cord blood, says the immediate require

PORTALEXCELLENCE: JOB PORTAL DEVELOPMENT OF MUNICIPAL EMPLOYMENT REPOSITORY - BROKERAGE, TRAINING, CONSULTANCY "Fresh News" First cord blood transplant to try to cure AIDS
Once a transplant can cure a viral illness such as leukemia and AIDS? This question had a positive answer in a German patient who contracted HIV (the AIDS virus) in 1995 and a year later she developed leukemia. In this patient we were in Berlin a bone marrow transplant from a donor who also had blood in his genetic variant of immunity to AIDS. I only did this combination effect, banishing his body the two diseases. Now another medical team, this time the United States has used a similar strategy to try to cure AIDS in a 12 years.
The little patient was born HIV positive and have the same fate that the German patient. A few months ago he developed leukemia, the most common childhood cancer, so doctors decided to try his luck with a strategy to fight simultaneously against the two evils. Cord instead of bone marrow.
They followed the German idea, but instead of taking a conventional bone marrow transplant, John Wagner and his team at the University of Minnesota in the small patient hand underwent a transplant of stem cells obtained from blood cord. These stem cells do not arouse any suspicion ethical and have the advantage over bone marrow causing less risk of rejection.
The cord blood is used either chose at random or thinking only compatible with the patient. Samples of the bank was looking for a very special, the one giving a natural protection against the AIDS virus. It is estimated that only 1 percent of the world population has a genetic characteristic that makes them immune to HIV infection. This mutation is called hand protective CCr5d32.
Before the transplant, the doctors put the patient in an aggressive treatment that involves cancel your immune system. For it endured chemotherapy and radiation. The goal was to transfuse the new cells, the immune system or defense reprogramarà. hand The transplant took place on April 23, but even a hundred days will not know if it has been successful. If the virus can not be detected hand in the blood of children, withdraw the medication and if undetected could still declared cured of AIDS. The best treatment.
John Wagner, director of the Transplant Program Blood and bone marrow Pediatrics, University of Minnesota, expressed his enthusiasm on the website of the university, hand although not sure if its bid was successful. "The most encouraging thing is that we demonstrate that AIDS can be cured and that the cord blood is the best treatment," says Wagner. "There are people hand with HIV and leukemia hand are awaiting the results as a breakthrough. Success in this patient could force the scientific community to find ways potentially safer and induce genetic variation in own stem cells from the bone marrow of patients. " This would generalize the treatment to larger number of patients.
Wagner, one of the biggest advocates of the use of umbilical cord blood, says the immediate requirement is to encourage cord blood banks to identify all blood units with varying resistance of HIV. " The case of baby healed. hand
Last month, another medical team from the United States announced a medical congress and had managed to cure a child with HIV, in another case that has also opened a new chapter in the history of AIDS.
The baby, a girl born in late 2010, received aggressive hand treatment with high doses of retroviral 30 hours of birth. The girl is now two and a half years and has been without medication for the last year without any signs of a registered active virus.
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