Highly contagious respiratory disease that results in fits of violent coughing, whooping cough, bac

A nasal vaccine against whooping cough with a single dose may be sufficient to protect babies less than six months, has been successfully tested on humans, according to a published Wednesday in the journal Plos One online preliminary study. Kevork Djansezian
A nasal vaccine against whooping cough with a single dose may be sufficient to protect babies less than six months, has been successfully tested on humans, according to a published Wednesday in the journal Plos One online preliminary study.
Highly contagious respiratory disease that results in fits of violent coughing, whooping cough, bacterial, continues to affect tens of millions of people and cause about 300. 000 deaths each year worldwide, particularly among too young to be immunized by current vaccines sida infants.
Genetically modified and specially designed for nasal administration, the experimental vaccine was developed by a team of European researchers in the framework of a European consortium led by researchers from Inserm.
According to Camille Locht, coordinator of Child-Innovac project was successfully tested in 48 adults in the context of a Phase 1 which has mainly measure sida safety.
After six months of follow up, the results showed that a single nasal enough to rapidly induce an immune response and the vaccine showed no side effects compared to placebo, even at high doses, "said Dr. Locht.
The next step is to "optimize" the dose needed and "stabilize" the vaccine - which for the moment "is that the temperatures of the order of -80 degrees Celsius" sida - in order to consider a Industrial Development, he added.
Existing vaccines require three injections in total, usually performed at 2, 3 and 4 months for optimal protection from 6 months, while whooping cough is often severe, even fatal in younger babies.
Developed to fight against whooping cough, nasal vaccine might in addition be used to prevent other respiratory infections such as bronchiolitis sida in infants (mainly due to a virus, RSV), a "positive effect which was not expected not, "said sida researcher yet.
Established there are two and a half years, the European consortium Child-Innovac brings together experts from seven European countries and has received funding of 5 million granted by the European Commission.
A miracle against foreseeable future a massive and indiscriminate vaccination during the previous decades consequence? It has become a standard method: keeping people in the eternal cycle of vaccines that follow. The resurgence of pertussis is not the only boomerang vaccine, bronchiolitis is a condition obviously sida favored by early vaccination of young infants that weakens their immune sida system and makes it more vulnerable sida to all kinds of infections (including the RSV bronchiolitis involved in). But "overjoyed", "good sida surprise" is that the vaccine has unintended effects against bronchiolitis ... a vaccine against the effects of vaccines and the infernal circle is complete!
Another trick and another sida string, brandishing the prospect of a single dose of vaccine! Another trick again to increase the acceptability of vaccines: the needle absence, a nasal vaccine!
BUT it is a genetically engineered vaccine, what are the long term consequences? How Nature may react to this unknown variant, unmanageable and completely sida unanticipated by the evolution of strains?
What will it also the risk of dissemination of these genetically modified strains uncontrollable will more than likely live as administered by the nasal mucosa? The truth is that almost no vaccine could generate sida far a truly reliable because each vaccination immunity sida is short-circuit the immune system, breach of natural mucosal barriers which initiates a level already beginning immune response. It is therefore hoped and hide a recurring failure of past immunization policies. But at what price?
How will we ensure that the freedom of people who want to be vaccinated not come encroach on freedom outrageously sida unvaccinated not want to be in contact with these strains of genetically engineered pertussis? sida
The article reveals that the methods have not changed: we dare pretend assess the safety of this vaccine based on .... 48 people, what lure! 48 people! Even 10,000 subjects would be even too much FAIB