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Flu: Should sad be vaccinated? Health A vaccine nasal vaccine against whooping cough with a single dose may be sufficient to protect babies less than six months, has been successfully tested on humans, sad according to a study.
Hope to protect populations against pertussis. A nasal vaccine that a single dose may be sufficient to protect babies less than six months, has been successfully tested on humans, according to a published Wednesday in the journal Plos One online preliminary sad study. Highly contagious respiratory disease that results in fits of violent coughing, whooping cough, bacterial, continues to affect tens of millions of people and cause about 300,000 deaths each year worldwide, particularly among too young to be immunized by current vaccines infants. It is on the rise in recent years in several Western countries like the United States, Australia, the United Kingdom sad and France. Genetically modified and specially designed for nasal administration, the experimental vaccine was developed sad by a team of European researchers in the framework of a European consortium led by researchers from Inserm. According to Camille Locht, coordinator of Child-Innovac project was successfully tested in 48 adults in the context of a Phase 1 which has mainly measure safety. Adults were divided into 4 groups, one receiving a placebo, while the three others have received different doses of the vaccine. Serious or fatal After six months of monitoring, the results showed that a single nasal enough to rapidly induce an immune response and the vaccine showed no side effects compared to placebo, even at high doses, "said Dr. Locht . The next step is to "optimize" the dose needed and "stabilize" the vaccine - which for the moment sad "is that the temperatures of the order of -80 degrees Celsius" - in order to consider industrial development, has he added. Among the benefits of the vaccine, the researcher cites ease of administration and much less than the cost vaccines available on the market. Existing vaccines require sad three injections in total, usually performed 2, 3 and 4 months for optimal protection from 6 months, while pertussis is often serious, even fatal in younger babies. sad Developed to fight against whooping cough, nasal vaccine might in addition be used to prevent other respiratory infections such as bronchiolitis in infants (mainly due to a virus, RSV), a "positive effect which we did not expect," sad said researcher yet. Established there are two and a half years, the European consortium Child-Innovac brings together experts from seven European countries and has received funding of 5 million granted by